SCHEMBL221839

SCHEMBL221839

Oc1cc(F)cc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29737584 1.00
SCHEMBL972239 0.78
SCHEMBL330662 0.78
SCHEMBL1155869 0.78
SCHEMBL1360451 0.78
SCHEMBL156265 0.78
SCHEMBL69832 0.78
1,3,5-Trichlorobenzene SCHEMBL7529975 0.76 TSHR (0.57)
Water SCHEMBL21493261 0.76 CA9 (0.93)
Water SCHEMBL16553164 0.76 TSHR (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240140915-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. 2024-05-02 US claimed
US-20240067612-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. 2024-02-29 US claimed
WO-2024010782-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. (US) 2024-01-11 WO claimed
US-10029992-B2 Diaminotriazine compounds and their use as herbicides BASF SE (DE) 2018-07-24 US claimed
EP-3134391-A1 DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2017-03-01 EP claimed
US-20170044114-A1 Diaminotriazine compounds and their use as herbicides BASF SE (DE) 2017-02-16 US claimed
WO-2015162166-A1 DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2015-10-29 WO claimed
US-20260091050-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY Atea Pharmaceuticals, Inc. (US) 2026-04-02 US disclosed
US-20250340508-A1 TETRAHYDRO-1H-CYCLOPENTA[CD]INDENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS NIKANG THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250326758-A1 RICYCLIC HETEROARYL DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2025-10-23 US disclosed
US-20250270188-A1 NLRP3 INFLAMMASOME INHIBITORS NOVARTIS AG (CH) 2025-08-28 US disclosed
EP-4402138-B1 3-PHENOXYAZETIDIN-1-YL-HETEROARYL PYRROLIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM INT (DE) 2025-08-27 EP disclosed
US-12391642-B2 Tetrahydro-1H-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors NIKANG THERAPEUTICS, INC. (US) 2025-08-19 US disclosed
WO-2002048124-A2 PIPERAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-06-20 WO disclosed
EP-0351615-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF Aktiengesellschaft (DE) 1992-10-28 EP disclosed
US-5072034-A PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
EP-0351615-A1 Process for the preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids BASF Aktiengesellschaft (DE) 1990-01-24 EP disclosed
EP-0102291-A1 Cephalosporin derivatives, their preparation and medicaments containing them RHONE-POULENC SANTE (FR) 1984-03-07 EP disclosed
US-4287125-A Preparation of benzenoid ethers and thioethers RHONE-POULENC INDUSTRIES (FR) 1981-09-01 US disclosed
US-4060562-A SULFUR CONTAINING CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed