Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22184970 | 0.94 | IDH1 (0.97) | IDH1NR1I2 | |
| SCHEMBL22184656 | 0.93 | IDH1 (0.98) | IDH1NR1I2 | |
| SCHEMBL22184650 | 0.92 | IDH1 (0.84) | IDH1NR1I2 | |
| SCHEMBL17814476 | 0.92 | IDH1 (1.00) | IDH1NR1I2 | |
| SCHEMBL19741810 | 0.92 | IDH1 (1.00) | IDH1NR1I2 | |
| SCHEMBL21466759 | 0.92 | IDH1 (0.84) | IDH1NR1I2 | |
| SCHEMBL17814493 | 0.92 | IDH1 (1.00) | IDH1NR1I2 | |
| SCHEMBL17814433 | 0.92 | IDH1 (1.00) | IDH1NR1I2 | |
| SCHEMBL17802995 | 0.92 | IDH1 (0.87) | IDH1NR1I2 | |
| SCHEMBL17814444 | 0.91 | IDH1 (1.00) | IDH1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226688-B1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES | MERCK SHARP & DOHME (US) | 2020-07-01 | — | — | EP | disclosed |