Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22185408 | 0.88 | HTR2A (0.39) | DHODHKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL19317570 | 0.85 | SLC6A2 (0.42) | DHODHSLC6A4 | |
| SCHEMBL12618091 | 0.81 | HTR2A (0.53) | DHODHHTR2ASLC6A4AR | |
| SCHEMBL22185406 | 0.81 | SLC6A4 (0.49) | DHODHHTR2ASLC6A4BCL2MCL1 | |
| SCHEMBL22199172 | 0.76 | SLC6A4 (0.42) | HTR2ASLC6A4LTA4HTSHRHRH1 | |
| SCHEMBL19317585 | 0.75 | SLC6A4 (0.41) | DHODHHTR2ASLC6A4LTA4HTSHR | |
| SCHEMBL18737242 | 0.75 | BCL2 (0.44) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL11584107 | 0.75 | PTGS1 (0.39) | HTR2ASLC6A4BCL2MCL1LTA4H | |
| SCHEMBL26866955 | 0.75 | PTGS1 (0.39) | DHODHBCL2MCL1LTA4HTSHR | |
| SCHEMBL6682183 | 0.75 | SLC6A4 (0.51) | HTR2ASLC6A4LTA4HTSHRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | DHODH 24/4885KCNQ3 2922/4885KCNQ2 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.