Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354267 | 0.88 | CYP19A1 (0.44) | SLC6A2SLC6A4SLC6A3HDAC1HDAC8 | |
| Water SCHEMBL10631653 | 0.79 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL9586018 | 0.77 | SMN1; SMN2 (0.44) | TRPA1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL3151286 | 0.77 | KMT2A (0.36) | TRPA1CYP2D6LMNAKMT2AATM | |
| SCHEMBL3840843 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL10839213 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| Water SCHEMBL28304858 | 0.76 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8730312 | 0.76 | SRC (0.58) | HDAC1HDAC8HDAC6CYP2D6SRC | |
| SCHEMBL27907795 | 0.76 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL144 | 0.76 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102477057-B | Thio-nicotinamide adenine dinucleotide, intermediates thereof and preparation methods of thio-nicotinamide adenine dinucleotide and intermediates | RES DEV CT OF BEIJING LEADMAN BIOCHEMICAL CO LTD | 2014-04-23 | — | — | CN | claimed |
| CN-102477057-A | Thioinamide adenine dinucleotide, intermediate thereof and preparation methods thereof | RES DEV CT OF BEIJING LEADMAN BIOCHEMICAL CO LTD | 2012-05-30 | — | — | CN | claimed |
| CN-103694251-B | A kind of new process preparing prasugrel hydrochloride | 南京简成医药科技有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-108137596-A | 1,2- dihydro -3H- pyrrolo-es [1,2-c] imidazoles -3- ketone antimicrobial compounds being substituted | 爱杜西亚药品有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-104024258-B | Pyrrolopyrazine kinase inhibitors | 霍夫曼-拉罗奇有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-104059173-B | A kind of supported late transition metal catalyst for vinyl polymerization | 中国石油化工股份有限公司 | 2016-09-21 | — | — | CN | disclosed |
| WO-2016144665-A1 | METHOD FOR PREPARING LARGAZOLE ANALOGS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2016-09-15 | — | — | WO | disclosed |
| CN-104059180-B | A kind of loaded late transition metal catalyst for vinyl polymerization | 中国石油化工股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104059175-B | A kind of for the supported late transition metal catalyst of vinyl polymerization, method for making and application | 中国石油化工股份有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-104059180-A | Supported transition-metal catalyst used for ethylene polymerization | CHINA PETROLEUM & CHEMICAL | 2014-09-24 | — | — | CN | disclosed |
| EP-0772459-A1 | TECHNETIUM-99m LABELED IMAGING AGENTS | DIATECH, INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0729648-A4 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LTD (AU) | 1997-01-02 | — | — | EP | disclosed |
| WO-1996035239-A1 | HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-11-07 | — | — | WO | disclosed |
| EP-0729648-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-09-04 | — | — | EP | disclosed |
| CN-1119867-A | Cephalosporin derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1996-04-03 | — | — | CN | disclosed |
| WO-1995029708-A1 | TECHNETIUM-99m LABELED IMAGING AGENTS | DIATECH, INC. (US) | 1995-11-09 | — | — | WO | disclosed |
| WO-1995012219-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1995-05-04 | — | — | WO | disclosed |
| EP-0271192-B1 | PURINE HISTAMINE H1 ANTAGONISTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0271192-A2 | Purine histamine H1 antagonists, their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |