Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28605682 | 0.99 | NOTUM (0.44) | NOTUMKDM1AIDH2F10PIM1 | |
| Hydrochloric Acid SCHEMBL28605683 | 0.99 | NOTUM (0.44) | NOTUMKDM1AIDH2F10PIM1 | |
| SCHEMBL22186378 | 0.92 | NOTUM (0.50) | NOTUMKDM1AF10DPP4HRH4 | |
| Hydrochloric Acid SCHEMBL28601658 | 0.90 | NOTUM (0.49) | NOTUMKDM1AF10DPP4HRH4 | |
| Hydrochloric Acid SCHEMBL28601661 | 0.90 | NOTUM (0.49) | NOTUMKDM1AF10DPP4HRH4 | |
| SCHEMBL14637698 | 0.85 | PIM1 (0.43) | NOTUMIDH2PIM1PIM2DPP4 | |
| SCHEMBL14637405 | 0.83 | NOTUM (0.48) | NOTUMIDH2F10AR | |
| SCHEMBL21624778 | 0.80 | NOTUM (0.64) | NOTUMDPP4AR | |
| SCHEMBL21624776 | 0.80 | NOTUM (0.64) | NOTUMDPP4AR | |
| SCHEMBL15117143 | 0.79 | AR (0.49) | NOTUMKDM1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138271-A1 | HETEROCYCLIC DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2020-07-02 | — | — | WO | disclosed |