Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.88 |
| ▸ | FGFR3 | P22607 | 10/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043296 | 0.94 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023073 | 0.90 | FGFR1 (0.88) | FGFR1FGFR3 | |
| SCHEMBL15043290 | 0.90 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043291 | 0.88 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043292 | 0.87 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043301 | 0.85 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043297 | 0.85 | FGFR1 (0.79) | FGFR1FGFR3 | |
| SCHEMBL15043289 | 0.85 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043303 | 0.84 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15046136 | 0.84 | FGFR1 (1.00) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268490-B1 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE-CONTAINING COMBINATIONS | Bayer Pharma AG (DE) | 2020-07-08 | — | — | EP | disclosed |