SCHEMBL22197477

SCHEMBL22197477

CCC(C)(C)CC(CC(C)(C)C)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.38
SLC6A2 P23975 4/20 0.38
SLC6A3 Q01959 4/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
LMNA P02545 4/20 0.38
CYP3A4 P08684 3/20 0.38
HRH3 Q9Y5N1 2/20 0.38
NPC1 O15118 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
MTOR P42345 2/20 0.38
RAB9A P51151 2/20 0.38
KCNK2 O95069 2/20 0.38
KCNH2 Q12809 2/20 0.38
CACNA1C Q13936 2/20 0.38
HTR2C P28335 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7060802 0.77 SLC6A4 (0.45) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL12958117 0.76 SLC6A4 (0.42) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL22197380 0.75 MAPT (0.38) SLC6A2MEN1KMT2ALMNACYP3A4
SCHEMBL22197476 0.73 SMN1; SMN2 (0.32) LMNASMN1; SMN2HPGD
SCHEMBL22197555 0.73 KDM4E (0.33) LMNANPC1RAB9AKDM4EMAPK1
SCHEMBL10875839 0.71 PPARG (0.43) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL10876391 0.71 SLC6A4 (0.41) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL15473214 0.68 SLC6A4 (0.44) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL6054793 0.68 SLC6A4 (0.42) SLC6A4SLC6A2SLC6A3MEN1KMT2A
SCHEMBL5405838 0.67 SLC6A4 (0.50) SLC6A4SLC6A2SLC6A3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3145911-B1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA L L C (US) 2020-07-08 EP disclosed