SCHEMBL22197816

SCHEMBL22197816

N#Cc1cc(I)c(N)c(I)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.58
ALB P02768 2/20 0.58
XDH P47989 1/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 1/20 0.34
VCAM1 P19320 2/20 0.33
TSHR P16473 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988148 0.84 TTR (0.48) TTRALBXDHCA1CA2
SCHEMBL1997670 0.84 TTR (0.48) TTRALBXDHCA1CA2
SCHEMBL2000379 0.84 TTR (0.48) TTRALBXDHCA1CA2
SCHEMBL2958367 0.84 TTR (0.54) TTRALBXDHMEN1KMT2A
SCHEMBL2949384 0.80 TTR (0.44) TTRALBXDHTSHRKDM4E
SCHEMBL31038060 0.78 TTR (0.64) TTRALBCA2CA9MEN1
SCHEMBL98131 0.75 TTR (0.48) TTRALBXDHCA1CA2
SCHEMBL5503660 0.74 TTR (0.43) TTRALBXDHTSHRCHRM2
Ioxynil SCHEMBL1701373 0.74 TTR (1.00) TTRALBCA2CA9MEN1
SCHEMBL11209099 0.74 TTR (0.58) TTRALBMEN1KMT2AVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535637-B2 Compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2022-12-27 US disclosed
US-20200216475-A1 COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535637-B2 Compound and organic light emitting element comprising same NR2E3, NR4A2, NR2C2 TTR 4279/4885ALB 4320/4885XDH 882/4885
US-20200216475-A1 COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME NR2E3, NR4A2, NR4A1 TTR 2849/4885ALB 3634/4885XDH 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.