Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.75 |
| ▸ | AR | P10275 | 18/20 | 0.74 |
| ▸ | GABRP | O00591 | 1/20 | 0.73 |
| ▸ | GABRD | O14764 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | KLK3 | P07288 | 1/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.73 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.73 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.73 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.73 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.73 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.73 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.73 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.73 |
| ▸ | GABRE | P78334 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456832 | 0.93 | ABCG2 (0.79) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL7035063 | 0.92 | AR (0.87) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL10073485 | 0.91 | AR (0.79) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL22198007 | 0.90 | ABCG2 (0.78) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL23260348 | 0.89 | ABCG2 (0.74) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL15506447 | 0.89 | ABCG2 (0.77) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL30431957 | 0.89 | ABCG2 (0.77) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL1444869 | 0.89 | ABCG2 (0.59) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL17941082 | 0.88 | ABCG2 (0.75) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL547391 | 0.88 | AR (0.84) | ABCG2ARGABRPGABRDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310083-A1 | FURAN FUSED RING-SUBSTITUTED GLUTARIMIDE COMPOUND | Medshine Discovery Inc. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-11834458-B2 | Anti-cancer nuclear hormone receptor-targeting compounds | NUVATION BIO INC. (US) | 2023-12-05 | — | — | US | disclosed |
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |
| WO-2020142228-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834458-B2 | Anti-cancer nuclear hormone receptor-targeting compounds | NCOA1, NCOR1, NCOA3 | ABCG2 350/4885AR 9/4885GABRP 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.