Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.61 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833384 | 0.84 | CYP4F2 (0.48) | CYP4A11CYP4F2GRIA4CA12CA1 | |
| SCHEMBL6565144 | 0.83 | GRIA4 (0.77) | GRIA4CA12CA1CA2CA9 | |
| SCHEMBL11171613 | 0.78 | CYP4A11 (0.63) | CYP4A11CYP4F2CA12CA1CA2 | |
| SCHEMBL11171618 | 0.78 | CYP4A11 (0.63) | CYP4A11CYP4F2CA12CA1CA2 | |
| SCHEMBL6563388 | 0.77 | GRIA4 (0.69) | GRIA4CA12CA1CA2CA9 | |
| SCHEMBL3977225 | 0.77 | CYP4A11 (1.00) | CYP4A11CYP4F2CA12CA1CA2 | |
| SCHEMBL5256710 | 0.77 | CYP4A11 (0.75) | CYP4A11CYP4F2CA12CA1CA2 | |
| SCHEMBL17315478 | 0.75 | CYP4A11 (0.73) | CYP4A11CYP4F2CA12CA1CA2 | |
| SCHEMBL5877603 | 0.75 | GRIA4 (0.67) | GRIA4CA12CA1CA2CA9 | |
| SCHEMBL7166935 | 0.75 | GRIA4 (0.66) | GRIA4CA12CA9CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216463-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | CYP4A11 4300/4885CYP4F2 4774/4885GRIA4 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.