Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20232255 | 0.97 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL14933345 | 0.97 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL14933524 | 0.97 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL14933564 | 0.95 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL14933369 | 0.95 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL14933400 | 0.94 | MAPK1 (0.63) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL15999724 | 0.94 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL22198480 | 0.93 | KDM4E (0.53) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL15999703 | 0.92 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL20632563 | 0.91 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216391-A1 | COMPOSITION FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216391-A1 | COMPOSITION FOR ORGANIC ELECTRONIC DEVICES | SLCO2B1, SLCO4C1, SLCO2A1 | MAPK1 4607/4885KDM4E 3376/4885L3MBTL1 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.