Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.65 |
| ▸ | BRD4 | O60885 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.51 |
| ▸ | ATAD2 | Q6PL18 | 5/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559601 | 0.83 | DAO (0.71) | DAOBRD4DDOATAD2KDM4E | |
| SCHEMBL22185215 | 0.79 | DAO (0.61) | DAOCA12CA9DDOAKR1B1 | |
| SCHEMBL866250 | 0.79 | DAO (0.65) | DAOBRD4DDOATAD2PARP1 | |
| SCHEMBL12970395 | 0.79 | DAO (0.65) | DAOBRD4CA12CA9DDO | |
| SCHEMBL3316092 | 0.79 | DAO (0.65) | DAOCA12CA9DDOAKR1B1 | |
| SCHEMBL16767858 | 0.79 | DAO (1.00) | DAOCA12CA9DDOAKR1B1 | |
| SCHEMBL31378942 | 0.79 | DAO (0.65) | DAOCA12CA9DDOAKR1B1 | |
| SCHEMBL24970979 | 0.79 | DAO (0.65) | DAODDOKDM4EHSD17B10 | |
| SCHEMBL22184925 | 0.78 | DAO (0.59) | DAOCA12CA9DDOAKR1B1 | |
| SCHEMBL837013 | 0.77 | DAO (0.53) | DAOCA12CA9DDOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |