Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 6/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22158820 | 0.98 | IDH1 (0.40) | CYP19A1IDH1PIM1CDC7CSNK2B | |
| SCHEMBL22185621 | 0.83 | DAO (0.57) | DAOHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30064571 | 0.81 | IDH1 (0.56) | IDH1DAO | |
| SCHEMBL17601235 | 0.81 | IDH1 (0.56) | IDH1DAO | |
| SCHEMBL17601233 | 0.81 | IDH1 (0.56) | IDH1DAO | |
| SCHEMBL17601343 | 0.81 | IDH1 (0.56) | IDH1DAO | |
| Hydrochloric Acid SCHEMBL22158939 | 0.81 | DAO (0.55) | DAOHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30064597 | 0.81 | IDH1 (0.56) | IDH1DAO | |
| Hydrochloric Acid SCHEMBL17601506 | 0.80 | IDH1 (0.55) | IDH1DAO | |
| Hydrochloric Acid SCHEMBL17601514 | 0.80 | IDH1 (0.55) | IDH1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |