Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22184957 | 0.91 | POLB (0.63) | ARGAAPOLBSLC22A12 | |
| SCHEMBL13074158 | 0.89 | AR (0.62) | ARGAAPOLBSLC22A12CYP1A2 | |
| SCHEMBL5949965 | 0.86 | AR (0.56) | ARGAAPOLBSLC22A12PLA2G7 | |
| SCHEMBL22199041 | 0.86 | AR (0.55) | ARGAAPOLBSLC22A12PLA2G7 | |
| SCHEMBL22184953 | 0.84 | AR (0.54) | ARGAAPOLBSLC22A12 | |
| SCHEMBL14081445 | 0.84 | AR (0.57) | ARSLC22A12PLA2G7 | |
| SCHEMBL22186126 | 0.84 | AR (0.54) | ARGAAPOLBSLC22A12CYP1A2 | |
| SCHEMBL16167721 | 0.83 | AR (0.70) | ARGAACYP1A2 | |
| SCHEMBL8631303 | 0.82 | AR (0.62) | AR | |
| SCHEMBL29681639 | 0.81 | GAA (0.74) | ARGAAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |