Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 11/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200400 | 0.89 | CLK1 (0.46) | STING1CLK1 | |
| SCHEMBL22200395 | 0.85 | STING1 (0.43) | STING1ACHE | |
| SCHEMBL22200292 | 0.85 | STING1 (0.46) | STING1 | |
| SCHEMBL22200618 | 0.85 | TP53 (0.43) | CLK1 | |
| SCHEMBL22200402 | 0.84 | STING1 (0.42) | STING1ACHE | |
| SCHEMBL22200414 | 0.84 | STING1 (0.47) | STING1ACHECLK1DYRK1AALOX5 | |
| SCHEMBL22200394 | 0.82 | STING1 (0.44) | STING1ACHE | |
| SCHEMBL22200401 | 0.81 | STING1 (0.40) | STING1ACHE | |
| SCHEMBL23999274 | 0.81 | STING1 (0.45) | STING1ACHE | |
| SCHEMBL22200283 | 0.80 | STING1 (0.58) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3907221-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020140894-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2020-07-09 | — | — | WO | disclosed |