Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 12/20 | 0.75 |
| ▸ | STK4 | Q13043 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780773 | 0.88 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL30478673 | 0.88 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL22076954 | 0.88 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL30478699 | 0.88 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL22076843 | 0.88 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL22076887 | 0.87 | EGFR (0.59) | EGFRERBB2STK4 | |
| SCHEMBL20780805 | 0.86 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL30478706 | 0.86 | EGFR (0.82) | EGFRERBB2 | |
| SCHEMBL20780762 | 0.86 | EGFR (0.82) | EGFRERBB2 | |
| SCHEMBL22076870 | 0.84 | EGFR (0.62) | EGFRERBB2STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677583-A1 | NITROGENOUS HETEROCYCLIC COMPOUND, PREPARATION METHOD, INTERMEDIATE, COMPOSITION, AND APPLICATION | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2020-07-08 | — | — | EP | disclosed |