Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | CETP | P11597 | 6/20 | 0.80 |
| ▸ | USP2 | O75604 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.75 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.75 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.75 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.75 |
| ▸ | CTSD | P07339 | 1/20 | 0.75 |
| ▸ | PTPRF | P10586 | 1/20 | 0.75 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.75 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.75 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.75 |
| ▸ | CES1 | P23141 | 1/20 | 0.75 |
| ▸ | ACP1 | P24666 | 1/20 | 0.75 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Acetylursolic Acid SCHEMBL23284101 | 1.00 | POLB (1.00) | POLBRECQLCETPUSP2MEN1 | |
| O-Acetylursolic Acid SCHEMBL22853927 | 1.00 | POLB (1.00) | POLBRECQLCETPUSP2MEN1 | |
| O-Acetylursolic Acid SCHEMBL10951133 | 1.00 | POLB (1.00) | POLBRECQLCETPUSP2MEN1 | |
| O-Acetylursolic Acid SCHEMBL827970 | 1.00 | POLB (1.00) | POLBRECQLCETPUSP2MEN1 | |
| O-Acetylursolic Acid SCHEMBL23793730 | 1.00 | POLB (1.00) | POLBRECQLCETPUSP2MEN1 | |
| SCHEMBL19472075 | 0.92 | POLB (0.85) | POLBRECQLCETPUSP2MEN1 | |
| SCHEMBL23793728 | 0.92 | POLB (0.85) | POLBRECQLCETPUSP2MEN1 | |
| SCHEMBL15713564 | 0.92 | POLB (0.85) | POLBRECQLCETPUSP2MEN1 | |
| SCHEMBL19472076 | 0.92 | POLB (0.85) | POLBRECQLCETPUSP2MEN1 | |
| SCHEMBL15163873 | 0.91 | POLB (0.83) | POLBRECQLCETPUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571354-B1 | Ursolic acid for inhibiting muscle atrophy | UNIV IOWA RES FOUND (US) | 2020-07-08 | — | — | EP | disclosed |