Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.66 |
| ▸ | ACP1 | P24666 | 2/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.61 |
| ▸ | PDE9A | O76083 | 1/20 | 0.61 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 6/20 | 0.57 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.55 |
| ▸ | IKBKB | O14920 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181569 | 0.92 | POLB (0.73) | PTPN1PTPN2ACP1PDE4DPDE5A | |
| SCHEMBL12181572 | 0.92 | POLB (0.73) | PTPN1PTPN2ACP1PDE4DPDE5A | |
| SCHEMBL31237280 | 0.92 | POLB (0.73) | PTPN1PTPN2ACP1PDE4DPDE5A | |
| SCHEMBL13523639 | 0.90 | PTPN1 (0.66) | PTPN1PTPN2ACP1PDE4DPDE5A | |
| SCHEMBL15163860 | 0.87 | POLB (0.67) | PTPN1PTPN2ACP1POLBRECQL | |
| SCHEMBL15163868 | 0.87 | POLB (0.67) | PTPN1PTPN2ACP1POLBRECQL | |
| SCHEMBL22201011 | 0.86 | PDE4D (0.55) | PTPN1PTPN2ACP1PDE4DPDE5A | |
| SCHEMBL22335282 | 0.86 | POLB (0.75) | PTPN1PTPN2ACP1POLBRECQL | |
| SCHEMBL3952674 | 0.84 | POLB (0.70) | PTPN1PTPN2ACP1POLBRECQL | |
| SCHEMBL13487368 | 0.83 | PDE4D (0.58) | PTPN1PTPN2ACP1PDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571354-B1 | Ursolic acid for inhibiting muscle atrophy | UNIV IOWA RES FOUND (US) | 2020-07-08 | — | — | EP | disclosed |