Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190389 | 1.00 | CHRM2 (0.56) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL1909819 | 0.91 | HCRTR2 (0.62) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL16796874 | 0.86 | HCRTR2 (0.64) | HCRTR2HCRTR1 | |
| SCHEMBL25017953 | 0.81 | CHRM2 (0.57) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL11477337 | 0.81 | CHRM2 (0.57) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL2118646 | 0.80 | CHRM2 (0.45) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL24508712 | 0.79 | CHRM2 (0.55) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL23513155 | 0.78 | CYP3A4 (0.50) | HCRTR2HCRTR1TP53MDM2TSHR | |
| SCHEMBL7407552 | 0.78 | HCRTR2 (0.50) | HCRTR2HCRTR1TP53MDM2EHMT2 | |
| SCHEMBL2265479 | 0.78 | HCRTR2 (0.50) | HCRTR2HCRTR1TP53MDM2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |