Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311352 | 0.73 | MAPT (0.60) | MAPTLMNAKMT2AMEN1TP53 | |
| SCHEMBL3309193 | 0.72 | MAPT (0.63) | MAPTLMNAKMT2AMEN1TP53 | |
| SCHEMBL3309188 | 0.70 | S1PR2 (0.66) | TP53 | |
| SCHEMBL3307423 | 0.69 | S1PR2 (0.57) | MAPTLMNAKMT2AMEN1TP53 | |
| SCHEMBL22693520 | 0.69 | S1PR2 (0.78) | MAPTLMNAKMT2AMEN1RXFP1 | |
| SCHEMBL3303804 | 0.68 | TP53 (0.54) | MAPTLMNAKMT2AMEN1RXFP1 | |
| SCHEMBL3316373 | 0.68 | TP53 (0.53) | MAPTLMNAKMT2AMEN1RXFP1 | |
| SCHEMBL13332657 | 0.67 | TP53 (0.53) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL13361508 | 0.67 | MEN1 (0.78) | MAPTLMNAKMT2AMEN1RXFP1 | |
| SCHEMBL3307491 | 0.66 | S1PR2 (0.69) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |