Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435992 | 0.89 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL6351496 | 0.88 | KMT2A (0.48) | KMT2ASMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL6343876 | 0.82 | CASR (0.47) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL2218687 | 0.81 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL6348536 | 0.80 | CASR (0.45) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL2219490 | 0.77 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL2215369 | 0.76 | MAPT (0.49) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL6594370 | 0.74 | KMT2A (0.75) | KMT2ASMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL17507489 | 0.74 | MAPT (0.54) | KMT2ASMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL6340685 | 0.73 | CA1 (0.52) | KMT2AMEN1ALDH1A1MAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351731-B1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2016-02-10 | — | — | EP | disclosed |
| EP-2351731-B1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2016-02-10 | — | — | EP | disclosed |
| US-8710098-B2 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Chinese Academy of Medical Science (CN) | 2014-04-29 | — | — | US | disclosed |
| EP-2351731-A1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2011-08-03 | — | — | EP | disclosed |
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Academy of Medical Science (CN) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | CUL3, APOBEC3G, BRPF3 | KMT2A 964/4885SMN1; SMN2 4598/4885LMNA 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.