Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10183405 | 0.68 | — | — | |
| SCHEMBL22191045 | 0.67 | HDAC3 (0.59) | CDK5CDK5R1AURKASYK | |
| SCHEMBL13839056 | 0.66 | CA1 (0.35) | — | |
| SCHEMBL12962757 | 0.63 | — | — | |
| SCHEMBL19062182 | 0.62 | KMT2A (0.45) | — | |
| SCHEMBL22191522 | 0.61 | LRRK2 (0.56) | AURKA | |
| SCHEMBL22191547 | 0.59 | SYK (0.60) | CDK5CDK5R1AURKASYK | |
| SCHEMBL22299742 | 0.58 | LRRK2 (0.47) | — | |
| SCHEMBL15729997 | 0.58 | — | — | |
| SCHEMBL737749 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142486-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2020-07-09 | — | — | WO | disclosed |