⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886157 | 0.93 | — | — | |
| SCHEMBL18758783 | 0.67 | CA12 (0.43) | — | |
| SCHEMBL2885783 | 0.67 | KDM4E (0.33) | — | |
| SCHEMBL2880035 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL2886428 | 0.66 | KMT2A (0.35) | — | |
| SCHEMBL1052780 | 0.66 | HDAC3 (0.53) | — | |
| SCHEMBL9055672 | 0.65 | CA12 (0.34) | — | |
| SCHEMBL28665273 | 0.65 | CA12 (0.34) | — | |
| SCHEMBL2883762 | 0.65 | MAPT (0.42) | — | |
| SCHEMBL7204430 | 0.65 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124489-B1 | THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN INC (US) | 2020-07-15 | — | — | EP | disclosed |