Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 4/20 | 0.47 |
| ▸ | BCL9 | O00512 | 4/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870379 | 1.00 | TRPV1 (0.52) | TRPV1MGLLBCL9CTNNB1FAAH | |
| SCHEMBL22207871 | 0.86 | BCL9 (0.44) | MGLLBCL9CTNNB1FAAHNOTUM | |
| SCHEMBL30870375 | 0.85 | TRPV1 (0.68) | TRPV1SOS1 | |
| SCHEMBL22207947 | 0.85 | TRPV1 (0.68) | TRPV1SOS1 | |
| SCHEMBL22207961 | 0.83 | TRPV1 (0.74) | TRPV1MGLLFAAHNOTUM | |
| SCHEMBL30870380 | 0.83 | TRPV1 (0.74) | TRPV1MGLLFAAHNOTUM | |
| SCHEMBL31478103 | 0.83 | TRPV1 (0.74) | TRPV1MGLLFAAHNOTUM | |
| SCHEMBL22207880 | 0.83 | TRPV1 (0.74) | TRPV1MGLLFAAHNOTUM | |
| SCHEMBL22207959 | 0.82 | TRPV1 (0.50) | TRPV1HSD11B1 | |
| SCHEMBL22207721 | 0.77 | TRPV1 (0.65) | TRPV1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272292-B | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2024-04-12 | — | — | CN | claimed |
| CN-113272292-A | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2021-08-17 | — | — | CN | claimed |
| CN-113272292-B | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2024-04-12 | — | — | CN | disclosed |
| EP-3908580-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2021-11-17 | — | — | EP | disclosed |
| CN-113272292-A | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020145831-A1 | (2,5-DIOXOPYRROLIDIN-L-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | Uniwersytet Jagielloński (PL) | 2020-07-16 | — | — | WO | disclosed |