SCHEMBL22209237

SCHEMBL22209237

NCCCCC(N)C(=O)OCC(O)CO

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.39
▸ DUSP3 P51452 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ DPP7 Q9UHL4 7/20 0.38
▸ DPP9 Q86TI2 4/20 0.38
▸ DPP8 Q6V1X1 3/20 0.38
▸ GNAI3 P08754 1/20 0.36
▸ GNAO1 P09471 1/20 0.36
▸ GNAI1 P63096 1/20 0.36
▸ DPP4 P27487 1/20 0.36
▸ RNPEP Q9H4A4 1/20 0.35
▸ CPB2 Q96IY4 1/20 0.35
▸ TLR2 O60603 2/20 0.34
▸ DGKA P23743 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17843610 1.00 GSR (0.48) GSRKDM4EDUSP3MEN1KMT2A
SCHEMBL3909526 0.88 GSR (0.50) GSRDPP7DPP9DPP8GNAI3
SCHEMBL6562358 0.88 GSR (0.50) GSRDPP7DPP9DPP8GNAI3
SCHEMBL6562360 0.88 GSR (0.50) GSRDPP7DPP9DPP8GNAI3
SCHEMBL1168273 0.86 GSR (0.42) GSRMEN1KMT2ADPP7DPP9
SCHEMBL29073349 0.83 KDM4E (0.59) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL29073213 0.83 KDM4E (0.59) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1168277 0.82 GSR (0.44) GSRLMNADPP7DPP9DPP8
SCHEMBL1168594 0.82 GSR (0.44) GSRLMNADPP7DPP9DPP8
SCHEMBL1167729 0.82 GSR (0.44) GSRLMNADPP7DPP9DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109112169-B Polylysine glyceride, preparation method and application thereof, and method for preparing polylysine 安泰生物工程股份有限公司 2021-12-14 — — CN disclosed
EP-3908601-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER Omeros Corporation (US) 2021-11-17 — — EP disclosed
US-20200345725-A1 Methods and Compositions for Treating Cancer OMEROS CORPORATOIN 2020-11-05 — — US disclosed
WO-2020146795-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION (US) 2020-07-16 — — WO disclosed
CN-109112169-A Polylysine glyceride and preparation method thereof, purposes and the method for preparing polylysine 武汉臻智生物科技有限公司 2019-01-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200345725-A1 Methods and Compositions for Treating Cancer LPAR5, LPAR3, LPAR1 GSR 425/4885KDM4E 3685/4885DUSP3 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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