Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20467320 | 1.00 | PTPN1 (0.42) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL18488372 | 1.00 | PTPN1 (0.42) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL6358667 | 1.00 | PTPN1 (0.42) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL10522832 | 0.87 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL3833437 | 0.87 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL13379049 | 0.87 | PTPN1 (0.48) | PTPN1FUCA1DRD2RECQLSMN1; SMN2 | |
| SCHEMBL6358553 | 0.87 | PTPN1 (0.45) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL22211395 | 0.86 | PTPN1 (0.44) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL500407 | 0.86 | PTPN1 (0.44) | PTPN1GBA1FUCA1DRD2RECQL | |
| SCHEMBL18453619 | 0.86 | PTPN1 (0.44) | PTPN1GBA1FUCA1DRD2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331886-B1 | DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A BICYCLO MOIETY | INDIVIOR UK LTD (GB) | 2020-07-15 | — | — | EP | disclosed |