SCHEMBL22212602

SCHEMBL22212602

Cn1ccc2c(Cc3ccc(Cl)nc3)cc(C(=O)NC3CCCCC3)nc21

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 6/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22212603 0.90 CHRM1 (0.63) CHRM1
SCHEMBL22212633 0.89 CHRM1 (0.62) CHRM1
SCHEMBL21545761 0.89 CHRM1 (0.77) CHRM1
SCHEMBL19932648 0.89 CHRM1 (0.50) CHRM1
SCHEMBL19932643 0.89 CHRM1 (0.64) CHRM1
SCHEMBL22212649 0.88 CHRM1 (0.60) CHRM1
SCHEMBL22212638 0.88 CHRM1 (0.60) CHRM1
SCHEMBL22212629 0.88 CHRM1 (0.48) CHRM1
SCHEMBL22212607 0.88 CHRM1 (0.55) CHRM1
SCHEMBL22212610 0.85 CHRM1 (0.63) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507289-B1 MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS SUVEN LIFE SCIENCES LTD (IN) 2020-07-15 EP disclosed