Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932716 | 1.00 | KMT2A (0.46) | KMT2APDE3BPDE3AHPGDSSCN9A | |
| SCHEMBL19932685 | 0.92 | NPC1 (0.46) | KMT2ANPC1RAB9ACHRM1CHRNB2 | |
| SCHEMBL22212630 | 0.90 | CHRM1 (0.40) | CHRM1CNR2 | |
| SCHEMBL19932683 | 0.90 | CHRM1 (0.48) | KMT2AHPGDSNPC1RAB9ACHRM1 | |
| SCHEMBL21545712 | 0.86 | CHRM1 (0.44) | KMT2ACHRM1 | |
| SCHEMBL21545762 | 0.86 | CHRM1 (0.51) | KMT2ACHRM1 | |
| SCHEMBL21545811 | 0.86 | CHRM1 (0.51) | KMT2ACHRM1 | |
| SCHEMBL21562949 | 0.86 | CHRM1 (0.51) | KMT2ACHRM1 | |
| SCHEMBL21545743 | 0.86 | CHRM1 (0.44) | KMT2ACHRM1 | |
| SCHEMBL19925647 | 0.86 | CHRM1 (0.51) | KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |