Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333902 | 0.86 | — | — | |
| SCHEMBL2198102 | 0.80 | — | — | |
| SCHEMBL6124697 | 0.78 | — | — | |
| SCHEMBL6515271 | 0.78 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL30832481 | 0.78 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL21224325 | 0.78 | — | — | |
| SCHEMBL7606324 | 0.77 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL28017797 | 0.77 | CYP2C19 (0.44) | CYP2C19SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL31336435 | 0.77 | CYP2C19 (0.44) | CYP2C19SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL8821789 | 0.76 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3679931-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, AND OTHER DISORDERS | Northwestern University (US) | 2020-07-15 | — | — | EP | disclosed |