Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22213636 | 0.80 | POLB (0.52) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL22762345 | 0.80 | MCL1 (0.53) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL18151726 | 0.75 | KMT2A (0.67) | MEN1KMT2APOLBALDH1A1PLAU | |
| SCHEMBL18151774 | 0.71 | PLAU (0.55) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL22213615 | 0.70 | MCL1 (0.64) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL18151899 | 0.70 | MCL1 (0.81) | MEN1KMT2APOLBPLAUGAA | |
| SCHEMBL22762666 | 0.70 | MCL1 (0.60) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL18152544 | 0.68 | PLAU (0.51) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL18151728 | 0.67 | BCL2L1 (0.49) | MEN1KMT2APOLBPLAUGAA | |
| SCHEMBL22213510 | 0.67 | MCL1 (0.50) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3680232-A1 | NOVEL ANTHRANILIC ACID-BASED COMPOUND, AND Pin1 INHIBITOR, THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES AND THERAPEUTIC AGENT FOR CANCER THAT USE THE SAME | Hiroshima University (JP) | 2020-07-15 | — | — | EP | disclosed |