Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21839508 | 1.00 | NT5E (0.80) | NT5ECD79B | |
| SCHEMBL21882835 | 1.00 | NT5E (0.80) | NT5ECD79B | |
| SCHEMBL22206534 | 0.93 | NT5E (0.81) | NT5E | |
| SCHEMBL19100689 | 0.89 | NT5E (1.00) | NT5E | |
| SCHEMBL19366690 | 0.89 | NT5E (1.00) | NT5E | |
| SCHEMBL23345957 | 0.88 | NT5E (0.76) | NT5ECD79B | |
| SCHEMBL26283322 | 0.88 | NT5E (0.76) | NT5ECD79B | |
| SCHEMBL23345956 | 0.88 | NT5E (0.76) | NT5ECD79B | |
| SCHEMBL23345568 | 0.85 | NT5E (0.78) | NT5E | |
| SCHEMBL23345570 | 0.85 | NT5E (0.78) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11058704-B2 | Inhibitors of adenosine 5′-nucleotidase | ARCUS BIOSCIENCES, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200222441-A1 | INHIBITORS OF ADENOSINE 5'-NUCLEOTIDASE | ARCUS BIOSCIENCES, INC. | 2020-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11058704-B2 | Inhibitors of adenosine 5′-nucleotidase | ENTPD5, NT5C2, ENTPD1 | NT5E 4/4885CD79B 2427/4885 |
| US-20200222441-A1 | INHIBITORS OF ADENOSINE 5'-NUCLEOTIDASE | ENTPD5, NT5C2, ENTPD1 | NT5E 4/4885CD79B 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.