⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21216094 | 1.00 | — | — | |
| SCHEMBL8975767 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL13213426 | 0.83 | ACE (0.39) | — | |
| SCHEMBL24494714 | 0.83 | ACE (0.39) | — | |
| SCHEMBL27250345 | 0.83 | ACE (0.39) | — | |
| SCHEMBL31510814 | 0.81 | ACE (0.42) | — | |
| SCHEMBL10166039 | 0.81 | HDAC7 (0.35) | — | |
| SCHEMBL20154135 | 0.81 | ANPEP (0.35) | — | |
| SCHEMBL24221392 | 0.81 | HDAC7 (0.35) | — | |
| SCHEMBL18494037 | 0.81 | CA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221867-A1 | Compounds Capable of Binding to Melanocortin 4 Receptor | NOVO NORDISK AS (DK) | 2021-07-22 | — | — | US | disclosed |
| US-20200223889-A1 | Bicyclic Compounds Capable of Binding to Melanocortin 4 Receptor | NOVO NORDISK A/S (DK) | 2020-07-16 | — | — | US | disclosed |