⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57549 | 0.97 | — | — | |
| Methane SCHEMBL222390 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL3496230 | 0.94 | — | — | |
| Lithium SCHEMBL17474380 | 0.94 | — | — | |
| Methane SCHEMBL190374 | 0.94 | — | — | |
| SCHEMBL12814542 | 0.86 | — | — | |
| Naphthalene SCHEMBL3488504 | 0.82 | CYP2A6 (0.38) | — | |
| Furan SCHEMBL2220476 | 0.80 | MAPK1 (0.36) | — | |
| Chlorobenzene SCHEMBL11324480 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL1229197 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3799871-A2 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOTOTIC BAX | Dana Farber Cancer Institute, Inc. (US) | 2021-04-07 | — | — | EP | claimed |
| US-20140357687-A1 | Pyrazol-3-ones That Activate Pro-apoptotic BAX | DANA FARBER CANCER INSTITUTE, INC. (US) | 2014-12-04 | — | — | US | claimed |
| EP-2766355-A2 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOPTOTIC BAX | Dana-Farber Cancer Institute, Inc. (US) | 2014-08-20 | — | — | EP | claimed |
| WO-2013055949-A2 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOPTOTIC BAX | DANA FARBER CANCER INSTITUTE, INC. (US) | 2013-04-18 | — | — | WO | claimed |
| CN-102696119-A | Rare earth removal of colorants | MOLYCORP MINERALS LLC | 2012-09-26 | — | — | CN | claimed |
| EP-0851288-B1 | Photographic element containing a 1,2,4,-Triazole-releasing pyrazolone DIR coupler | EASTMAN KODAK CO (US) | 2000-04-05 | — | — | EP | claimed |
| US-5965341-A | IMPROVED INTERIMAGE OF A GREEN SENSITIZED LAYER IN A MULTICOLOR SILVER HALIDE PHOTOGRAPHIC ELEMENT CONTAINING BOTH A PYRAZOLONE MAGENTA IMAGE DYE-FORMING DIR COUPLER AND ANOTHER SIMILAR COUPLER; CONTRAST; SHARPNESS; STABILITYINTERIMAGE THAN | EASTMAN KODAK COMPANY (US) | 1999-10-12 | — | — | US | claimed |
| US-5958662-A | PYRAZOLONE DERIVATIVES; STABILITY | EASTMAN KODAK COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| US-5821043-A | DEVELOPMENT INHIBITOR RELEASING COUPLERS | EASTMAN KODAK COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| EP-0867764-A1 | Photographic element containing a dir coupler | EASTMAN KODAK COMPANY (US) | 1998-09-30 | — | — | EP | claimed |
| EP-0851288-A1 | Photographic element containing a 1,2,4,-Triazole-releasing pyrazolone DIR coupler | EASTMAN KODAK COMPANY (US) | 1998-07-01 | — | — | EP | claimed |
| US-4013633-A | Yellow azopyrazoline dye releasing redox compounds for photographic color transfer | EASTMAN KODAK COMPANY (US) | 1977-03-22 | — | — | US | claimed |
| CN-119977978-A | Catalytic synthesis method of chiral pyrazolo hydro-pyran compound | 中国海洋大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-118345388-A | Method for preparing pyrazolone substituted quinoxalinone derivative through electrochemical promotion | 桂林理工大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-3799871-B1 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOTOTIC BAX | DANA FARBER CANCER INST INC (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-114262281-B | Separation method of pyrazoline isomer mixture by using polar solvent-resistant nanofiltration membrane | 郑州大学 | 2023-05-23 | — | — | CN | disclosed |
| US-5674669-A | CONTAINS A MONOMETHINE PYRAZOLONE OXONOL DYE WITH A 1-PHENYL GROUP BEARING A SULFO OR SULFATO SUBSTITUENT | EASTMAN KODAK COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0740200-A1 | Photographic elements containing oxonol filter dye mixture and their preparation | EASTMAN KODAK COMPANY (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5001220-A | Pyrazolone substituted copolyarylene sulfide | BAYER AG (DE) | 1991-03-19 | — | — | US | disclosed |
| US-4013633-A | Yellow azopyrazoline dye releasing redox compounds for photographic color transfer | EASTMAN KODAK COMPANY (US) | 1977-03-22 | — | — | US | disclosed |