⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14814100 | 1.00 | — | — | |
| SCHEMBL14814592 | 1.00 | — | — | |
| SCHEMBL704726 | 0.73 | — | — | |
| SCHEMBL2779132 | 0.73 | — | — | |
| SCHEMBL7273969 | 0.71 | — | — | |
| Ethylene SCHEMBL892064 | 0.71 | MAPK1 (0.42) | — | |
| SCHEMBL14000783 | 0.69 | — | — | |
| SCHEMBL147241 | 0.69 | — | — | |
| SCHEMBL5791362 | 0.69 | — | — | |
| SCHEMBL515418 | 0.69 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3124 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898286-A | Benzothiophene compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2021-06-04 | — | — | CN | claimed |
| EP-3210469-A1 | USE OF SUBSTITUTED THIO-1,2,4-TRIAZOLES FOR INCREASING STRESS TOLERANCE IN PLANTS | Bayer Cropscience AG (DE) | 2017-08-30 | — | — | EP | claimed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | claimed |
| CN-101374844-B | Pyrrolopyridazinone compound | UBE INDUSTRIES | 2012-10-24 | — | — | CN | claimed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | claimed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | claimed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | claimed |
| CN-101346361-A | Compound (I) | ASTRAZENECA AB (SE) | 2009-01-14 | — | — | CN | claimed |
| US-20080312206-A1 | Chemical Compounds-149 | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | claimed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | claimed |
| EP-1966174-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | claimed |
| WO-2007071955-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | claimed |
| EP-0086750-B1 | USE OF QUINOLINE DERIVATIVES IN THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | claimed |
| US-4015012-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | claimed |
| US-3970699-A | 4-Acylaminophenylacetamidines and a method for their preparation | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | claimed |
| US-20240239842-A1 | BINDING MOLECULE EXHIBITING SELECTIVE BINDING FOR RAS(G12D) MUTANT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-07-18 | — | — | US | disclosed |
| US-12037326-B2 | Diaryl-azole compound and formulation for controlling harmful organism | NIPPON SODA CO., LTD. (JP) | 2024-07-16 | — | — | US | disclosed |
| US-4294971-A | Preparation of N-aryloxazolidine-2,4-diones | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |
| US-3941804-A | 1-Heteroarylsulphonyl-2-imino-imidazolidines | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |