Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22220708 | 0.94 | KRAS (0.75) | KRAS | |
| SCHEMBL22555139 | 0.93 | KRAS (0.69) | KRAS | |
| SCHEMBL22555042 | 0.93 | KRAS (0.69) | KRAS | |
| SCHEMBL30065080 | 0.90 | KRAS (0.66) | KRAS | |
| SCHEMBL22220048 | 0.90 | KRAS (0.66) | KRAS | |
| SCHEMBL22555141 | 0.90 | KRAS (0.66) | KRAS | |
| SCHEMBL22220551 | 0.90 | KRAS (0.66) | KRAS | |
| SCHEMBL22554983 | 0.90 | KRAS (0.74) | KRAS | |
| SCHEMBL22586660 | 0.90 | KRAS (0.66) | KRAS | |
| SCHEMBL30070957 | 0.90 | KRAS (0.66) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146613-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |