Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220224 | 0.87 | F10 (0.57) | F10F2KLK1 | |
| SCHEMBL222823 | 0.84 | F10 (0.59) | F10F2MAPK1 | |
| SCHEMBL222531 | 0.83 | F10 (0.60) | F10MAPK1 | |
| SCHEMBL221193 | 0.81 | F10 (0.69) | F10MAPK1 | |
| SCHEMBL220475 | 0.80 | F10 (0.67) | F10MAPK1 | |
| SCHEMBL222060 | 0.79 | F10 (0.55) | F10F2KLK1 | |
| SCHEMBL222611 | 0.79 | F10 (0.66) | F10MAPK1 | |
| SCHEMBL2737094 | 0.78 | F10 (0.63) | F10MAPK1 | |
| SCHEMBL219860 | 0.78 | F10 (0.65) | F10MAPK1 | |
| SCHEMBL219872 | 0.77 | F10 (0.63) | F10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |