Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 19/20 | 0.45 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22224174 | 0.93 | NR1H2 (0.45) | NR1H2NR1H3SOD1 | |
| SCHEMBL21569826 | 0.85 | NR1H2 (0.41) | NR1H2NR1H3 | |
| SCHEMBL21569982 | 0.84 | NR1H2 (0.54) | NR1H2NR1H3SOD1 | |
| SCHEMBL22224316 | 0.84 | NR1H2 (0.63) | NR1H2NR1H3SOD1 | |
| SCHEMBL21569906 | 0.82 | NR1H2 (0.48) | NR1H2NR1H3SOD1 | |
| SCHEMBL21569812 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3SOD1 | |
| SCHEMBL21569769 | 0.79 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL29292396 | 0.79 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL21569788 | 0.78 | NR1H2 (0.53) | NR1H2NR1H3SOD1 | |
| SCHEMBL29292405 | 0.78 | NR1H2 (0.49) | NR1H2NR1H3SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146541-A2 | TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-16 | — | — | WO | disclosed |