Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355557 | 1.00 | PDK2 (0.48) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22037598 | 0.93 | PDK2 (0.47) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL20809932 | 0.93 | PDK2 (0.50) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL20809920 | 0.93 | PDK2 (0.50) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22038366 | 0.91 | PDK2 (0.46) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22038471 | 0.91 | PDK2 (0.45) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22037624 | 0.91 | PDK2 (0.45) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22037438 | 0.91 | PDK2 (0.45) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22039018 | 0.91 | PDK2 (0.45) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL22037893 | 0.91 | PDK2 (0.45) | PDK2CYP19A1DHODHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277272-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| EP-3683212-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2020-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277272-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE | SLC29A1, ADORA1, SLC29A2 | PDK2 2822/4885CYP19A1 1296/4885DHODH 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.