SCHEMBL22228577

SCHEMBL22228577

CCO[Si](CCCOCC(O)COCC(F)(F)F)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.40
HSD17B10 Q99714 2/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
USP2 O75604 1/20 0.35
HTT P42858 1/20 0.34
LPAR5 Q9H1C0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167772 0.84 USP2 (0.41) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL9411706 0.84 CES1 (0.34) PLA2G2C
SCHEMBL13922639 0.83 USP2 (0.40) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL29039757 0.83 USP2 (0.40) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL16545849 0.81 USP2 (0.39) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL29974664 0.80 USP2 (0.38) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL4205822 0.80 USP2 (0.56) PLA2G2CHSD17B10CYP2C19USP2HTT
SCHEMBL28464049 0.78 USP2 (0.42) PLA2G2CHSD17B10CYP2C19USP2HTT
SCHEMBL13922636 0.78 USP2 (0.39) HSD17B10CYP2C19USP2HTTLPAR5
SCHEMBL29912616 0.78 CES1 (0.40) PLA2G2CHSD17B10CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075101-A1 SURFACE TREATMENT Interphase Materials, Inc (US) 2025-03-06 US disclosed
US-12146071-B2 Surface treatment INTERPHASE MATERIALS INC. (US) 2024-11-19 US disclosed
US-20200231842-A1 Surface Treatment INTERPHASE MAT INC (US) 2020-07-23 US disclosed