Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785978 | 1.00 | S1PR4 (0.33) | S1PR4KCNN4ADORA2AADORA1MAPT | |
| SCHEMBL16238204 | 0.81 | S1PR4 (0.33) | S1PR4KCNN4XDH | |
| SCHEMBL16742675 | 0.80 | S1PR4 (0.34) | S1PR4ADORA2AADORA1MAPTXDH | |
| SCHEMBL30082515 | 0.80 | S1PR4 (0.34) | S1PR4ADORA2AADORA1MAPTXDH | |
| SCHEMBL5455137 | 0.79 | NQO2 (0.39) | MAPT | |
| SCHEMBL31556399 | 0.79 | NQO2 (0.39) | MAPT | |
| SCHEMBL2370651 | 0.79 | CLCN2 (0.35) | S1PR4KCNN4XDH | |
| SCHEMBL28566471 | 0.79 | KMT2A (0.33) | S1PR4ADORA2AADORA1MAPTXDH | |
| SCHEMBL24992633 | 0.77 | S1PR4 (0.33) | S1PR4ADORA2AADORA1MAPTXDH | |
| SCHEMBL30865588 | 0.77 | S1PR4 (0.33) | S1PR4ADORA2AADORA1MAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771027-B | Lysophosphatidic acid receptor antagonists and process for preparing the same | 武汉朗来科技发展有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-112771027-A | Lysophosphatidic acid receptor antagonists and process for their preparation | 武汉朗来科技发展有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |