Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.40 |
| ▸ | FASN | P49327 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559937 | 0.76 | FASN (0.68) | NAMPTFASNSMN1; SMN2PIK3C3MEN1 | |
| SCHEMBL4561010 | 0.74 | FASN (0.49) | NAMPTFASNSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4542038 | 0.70 | FASN (0.51) | NAMPTFASNPIK3C3 | |
| SCHEMBL15238750 | 0.67 | FASN (0.63) | NAMPTFASNSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3190627 | 0.65 | FLT3 (0.48) | NAMPTPIK3C3 | |
| SCHEMBL14826051 | 0.64 | PIK3C3 (0.51) | PIK3C3CCNCCDK8CDK19MEN1 | |
| SCHEMBL4562178 | 0.64 | FASN (0.64) | NAMPTFASN | |
| SCHEMBL21364619 | 0.61 | PIK3C3 (0.46) | SMN1; SMN2PIK3C3ALDH1A1QPCT | |
| SCHEMBL3321465 | 0.61 | FLT3 (0.48) | PIK3C3QPCT | |
| SCHEMBL23068965 | 0.59 | CHRNA7 (0.47) | SMN1; SMN2PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |