Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832666 | 0.90 | TACR1 (0.46) | TACR1DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL22623154 | 0.88 | MAPT (0.51) | TACR1DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL22227848 | 0.85 | TACR1 (0.44) | TACR1DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL14154859 | 0.81 | DRD4 (0.51) | TACR1DRD4MEN1KMT2AGAA | |
| SCHEMBL1553056 | 0.80 | TACR1 (0.56) | TACR1MEN1KMT2ACLPP | |
| SCHEMBL1551999 | 0.78 | TACR1 (0.56) | TACR1SIGMAR1MEN1KMT2ACLPP | |
| SCHEMBL5968243 | 0.78 | TACR1 (0.56) | TACR1DRD2DRD3SIGMAR1 | |
| SCHEMBL5667214 | 0.78 | TACR1 (0.56) | TACR1DRD2DRD3SIGMAR1 | |
| SCHEMBL1553263 | 0.77 | TACR1 (0.53) | TACR1DRD4 | |
| SCHEMBL6493798 | 0.76 | TACR1 (0.43) | TACR1DRD4DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682881-A1 | COMPOUND HAVING CYCLIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-07-22 | — | — | EP | disclosed |