Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.37 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.30 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.30 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.30 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.30 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22241014 | 0.87 | APP (0.39) | APPPRF1FEN1CYP1A1CYP1A2 | |
| SCHEMBL21134077 | 0.85 | APP (0.40) | APPPRF1ERCC5FEN1CYP1A1 | |
| SCHEMBL18418554 | 0.81 | ERCC5 (0.32) | APPERCC5FEN1CYP1A2CYP3A4 | |
| SCHEMBL16265228 | 0.80 | APP (0.36) | APPPRF1ERCC5FEN1 | |
| SCHEMBL19636897 | 0.79 | — | — | |
| SCHEMBL22241066 | 0.76 | APP (0.33) | APPPRF1 | |
| SCHEMBL20647416 | 0.76 | APP (0.33) | APPPRF1 | |
| SCHEMBL21134088 | 0.76 | APP (0.33) | APPERCC5FEN1 | |
| SCHEMBL20806064 | 0.76 | NR1H4 (0.42) | APPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17694348 | 0.75 | APP (0.43) | APPPRF1CYP1A1CYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-3400271-B1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |