Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826328 | 0.91 | PIK3CD (0.42) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13828422 | 0.85 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13717681 | 0.85 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL16589441 | 0.85 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL29895849 | 0.85 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13825936 | 0.82 | AR (0.42) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13826309 | 0.82 | PIK3CD (0.42) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13718119 | 0.82 | PIK3CD (0.42) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13826607 | 0.80 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E | |
| SCHEMBL13828449 | 0.80 | PIK3CD (0.40) | PIK3CDPIK3CGARPIK3R1CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844647-B1 | PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2-(1-HYDROXY-ALKYL)-CHROMEN-4-ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS | RHIZEN PHARMACEUTICALS S A (CH) | 2020-07-22 | — | — | EP | disclosed |