Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136364 | 1.00 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL29346469 | 1.00 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL24136363 | 0.85 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL20090887 | 0.85 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL24270955 | 0.85 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL24136421 | 0.85 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL24136420 | 0.85 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL24136467 | 0.84 | ESR1 (0.51) | GRIN2BGRIN1 | |
| SCHEMBL24136464 | 0.84 | ESR1 (0.51) | GRIN2BGRIN1 | |
| SCHEMBL16600915 | 0.81 | GRIN2B (1.00) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150146-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | NOVARTIS AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| EP-3974420-B1 | N-ALKYLARYL-5-OXYHETEROARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | NOVARTIS AG (CH) | 2023-08-16 | — | — | EP | disclosed |
| EP-3683207-B1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-3683207-A1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |