Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031692 | 0.81 | TSHR (0.40) | TSHRTDP1 | |
| SCHEMBL17615147 | 0.81 | TSHR (0.40) | TSHRTDP1 | |
| SCHEMBL6383291 | 0.75 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL8370669 | 0.75 | TSHR (0.44) | TSHRTDP1 | |
| SCHEMBL20785659 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL31885 | 0.73 | — | — | |
| SCHEMBL14492137 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL3386274 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL14255589 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL6854731 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |