Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208655 | 0.89 | EPHX2 (0.50) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL22240360 | 0.82 | EPHX2 (0.52) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL20209068 | 0.81 | EPHX2 (0.51) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL27573321 | 0.80 | TACR1 (0.53) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL27478679 | 0.80 | TACR1 (0.53) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL6371364 | 0.80 | TACR1 (0.53) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL20208583 | 0.79 | EPHX2 (0.49) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL14847452 | 0.77 | PPARG (0.52) | EPHX2PPARGMAPTTDP1TSHR | |
| SCHEMBL22240190 | 0.77 | KDM4E (0.52) | EPHX2PPARGNOS2NOS3NOS1 | |
| SCHEMBL6277159 | 0.77 | EPHX2 (0.53) | EPHX2PPARGNOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280721-B1 | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES | ONCOPEPTIDES AB (SE) | 2020-07-22 | — | — | EP | disclosed |