Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22243337 | 0.87 | BTK (0.44) | BTK | |
| SCHEMBL22243334 | 0.87 | BTK (0.44) | BTK | |
| SCHEMBL22243271 | 0.86 | BTK (0.41) | BTK | |
| SCHEMBL22243291 | 0.85 | BTK (0.42) | BTKLCK | |
| SCHEMBL22243275 | 0.84 | BTK (0.41) | BTK | |
| SCHEMBL24041337 | 0.81 | BTK (0.40) | BTKLCK | |
| SCHEMBL24041317 | 0.78 | BTK (0.35) | BTKLCK | |
| SCHEMBL25466292 | 0.76 | CYP2C19 (0.46) | BTKLCK | |
| SCHEMBL24041280 | 0.76 | BTK (0.43) | BTKLCK | |
| SCHEMBL22243339 | 0.75 | BTK (0.37) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147798-A1 | CYCLIC MOLECULES AS BRUTON'S TYROSINE KINASE INHIBITOR | 明慧医药（上海）有限公司 | 2020-07-23 | — | — | WO | disclosed |