SCHEMBL2224519

SCHEMBL2224519

C=C(C)C(=O)OCCCCCCOc1ccc(/C=C\C(=O)OCCCCCCCCCCCCCCCC)cc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
APEX1 P27695 1/20 0.57
HTT P42858 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
APP P05067 5/20 0.57
TSHR P16473 3/20 0.56
ABCG2 Q9UNQ0 1/20 0.49
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ESR1 P03372 1/20 0.45
BCHE P06276 2/20 0.45
ACHE P22303 1/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2224525 1.00 POLB (0.57) POLBAPEX1HTTTDP1APP
SCHEMBL12516446 1.00 POLB (0.57) POLBAPEX1HTTTDP1APP
SCHEMBL12517246 1.00 POLB (0.57) POLBAPEX1HTTTDP1APP
SCHEMBL2223306 1.00 POLB (0.57) POLBAPEX1HTTTDP1APP
SCHEMBL25634616 0.98 TDP1 (0.54) POLBAPEX1HTTTDP1APP
SCHEMBL14926800 0.98 TDP1 (0.54) POLBAPEX1HTTTDP1APP
SCHEMBL12517639 0.93 TDP1 (0.53) POLBAPEX1HTTTDP1APP
SCHEMBL9952390 0.92 POLB (0.58) POLBAPEX1HTTTDP1APP
SCHEMBL9952394 0.92 POLB (0.58) POLBAPEX1HTTTDP1APP
SCHEMBL12517641 0.91 TDP1 (0.57) POLBAPEX1HTTTDP1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362151-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2013-01-29 US disclosed
EP-2513157-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS Li, Chunhong (US) 2012-10-24 EP disclosed
WO-2011084546-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS LI CHUNHONG (US) 2011-07-14 WO disclosed
US-20100305230-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2010-12-02 US disclosed
US-6919404-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2005-07-19 US disclosed
US-20030232930-A1 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. 2003-12-18 US disclosed
WO-2003102045-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2003-12-11 WO disclosed