SCHEMBL22245502

SCHEMBL22245502

O=CCOCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.62
▸ NOD1 Q9Y239 2/20 0.42
▸ CCKAR P32238 5/20 0.41
▸ CCKBR P32239 5/20 0.41
▸ FOLH1 Q04609 3/20 0.40
▸ GLO1 Q04760 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18885578 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL15369019 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL2373708 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL21242756 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL23081524 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL18885624 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24899308 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL25454272 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL22245528 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL2040679 1.00 GLP1R (0.62) GLP1RNOD1CCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130794-B2 Bifunctional compounds NOVO NORDISK A/S (DK) 2021-09-28 — — US disclosed
US-20200231645-A1 Bifunctional compounds NOVO NORDISK A/S (DK) 2020-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130794-B2 Bifunctional compounds GLP1R, PCSK9, PCSK7 GLP1R 1/4885NOD1 743/4885CCKAR 26/4885
US-20200231645-A1 Bifunctional compounds GLP1R, PCSK9, PCSK7 GLP1R 1/4885NOD1 743/4885CCKAR 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback